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Est. 1997 · Clinical software & services

Three decades of clinical SAS expertise.
Now with an agent in the loop.

Meta-Xceed, Inc. (MXI) builds software and delivers services for pharmaceutical, biotech, CRO, and medical-device teams — from CDISC data transformation to regulatory submission. Our flagship product, DoLoup, brings agentic AI automation to clinical statistical programming.

Trusted standards, regulated environments

CDISC Registered Solutions Provider SAS Alliance Partner 21 CFR Part 11 GAMP 5 SDTM · ADaM SAS 9.4 · R
Flagship product

DoLoup — the agent that loops until your log is clean

DoLoup writes the SAS program, runs it, reads the real log, fixes the ERRORs — and loops until it's clean. Then it QCs every dataset against your CDISC checklist with an independent validation program written by a different AI model.

  • Agentic correction loops: build → run → read log → fix, hands-free
  • Checklist-driven CDISC QC with Pass/Fail CSV reports
  • Dual-model double programming — production and validation stay independent
  • Git-backed versioning and a full audit trail for regulated work

See DoLoup in action →

DoLoup — agentic loop · ae.sas ● live
*** %do %until (log_clean) ***;
pass 1 → 3 ERRORS  → fixing…
pass 2 → 1 WARNING → fixing…
pass 3 → log clean ✓  %end;

*** QC: v_ae.sas · SDTM IG v3.3 ***;
NOTE: Total checks: 25 Passed: 23 Failed: 2
NOTE: AE_SDTMIG33_Validation_Report.csv
What we do

From phase 1 to submission

A senior team supporting clinical programs across the full regulatory lifecycle.

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CDISC data transformation

SDTM and ADaM conversion, define.xml data definition, and submission-ready deliverables aligned to your IG version.

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Statistical programming

SAS 9.4 and R programming for tables, listings, and figures — accelerated by DoLoup's agentic automation.

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Biostatistics

Analysis planning, statistical review, and support for electronic submissions to regulatory agencies.

🖥️

Statistical computing environments

SAS server installation on-premise or cloud, IQ/OQ/PQ validation documentation, and tooling like Pinnacle 21 and R.

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Data management

CRF design, database builds, discrepancy management, and delivery in CDISC models.

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Custom software & validation

Purpose-built clinical software with 21 CFR Part 11 compliance and full validation documentation.

All services →

Meta-Xceed in numbers

Experience you can audit

Clinical data expertise built study by study since 1997.

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Years in clinical software
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Part 11 · GAMP 5 aligned
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Flagship product: DoLoup
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Manual log reviews
Ready when you are

Put an agent in your loop

Talk to us about DoLoup, or about supporting your next study from raw data to submission.

Contact Meta-Xceed   Explore DoLoup